I suppose therefore that

I suppose therefore that all things I see are illusions; I believe that nothing has ever existed of everything my lying memory tells me. I think I have no senses. I believe that body, shape, extension, motion, location are functions. What is there then that can be taken as true? Perhaps only this one thing, that nothing at all is certain.
Rene Descartes

For those [observations] that

For those [observations] that I made in Leipzig in my youth and up to my 21st year, I usually call childish and of doubtful value. Those that I took later until my 28th year [i.e., until 1574] I call juvenile and fairly serviceable. The third group, however, which I made at Uraniborg during approximately the last 21 years with the greatest care and with very accurate instruments at a more mature age, until I was fifty years of age, those I call the observations of my manhood, completely valid and absolutely certain, and this is my opinion of them.
Tycho Brahe